Accolate (Zafirlukast) for asthma | MyAsthmaTeam

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Accolate is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat asthma in adults and children 5 years of age and older. Accolate is also referred to by its drug name, zafirlukast.

Accolate is a member of a class of drugs called leukotriene inhibitors, specifically a leukotriene receptor antagonist. Accolate is believed to work by reducing the production of leukotrienes in the body. Leukotrienes are chemicals involved in airway edema (swelling), smooth muscle contraction, and other processes associated with the symptoms of asthma. Inhibiting their production helps to relieve these symptoms.

How do I take it?
Prescribing information states that, for adults and children 12 and older, Accolate should be taken orally as a tablet twice daily, at least one hour before or two hours after meals.

Accolate should be taken exactly as prescribed by a physician.

Side effects
The FDA-approved label for Accolate lists common side effects including headache, infection, diarrhea, nausea, weakness, fever, and abdominal pain.

Rare but serious side effects listed for Accolate include liver failure, insomnia, depression, and eosinophilic conditions.

For more details about this treatment, visit:

Accolate — U.S. Food and Drug Administration

Zafirlukast (Oral Route) — Mayo Clinic

Accolate — RxList

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